7.  Polyethylene Glycol Used in a Study Regarding the In Vivo Effects of the Organometallic Gallium Complex C(85)

Authors: G. Garban, N. Hadaruga, C. Balta, G.D. Ghibu, C. Mitar, Z. Garban and E. Simiz


Abstract:

The paper presents the use of polyethylene glycol (PEG) in a solvent mixture for solubilizing the organometallic gallium complex C (85) in order to investigate its effects on an animal experimental model. Changes of biochemical homeostasis of certain blood parameters revealed the effects induced by the intraperitoneally administered Ga complex in Wistar strain rats in two different period of day. In this regard there were detected changes in serum protein and albumin as well as in serum calcium and magnesium. Variations were noticed also in the concentration of non-protein nitrogenous substances (uric acid, creatinine and blood urea nitrogen).


Keywords: PEG - gallium complex, in vivo experiment

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